The Harrison County Sheriff's Office told media outlets on Thursday that a woman, also in the Clearfork Road residence when the fire began, succumbed to her injuries in a Pittsburgh-area burn center on Thursday morning. That woman is the mother of two children, aged 6 and 7, who died on Wednesday.
Two others were transported to local hospitals, one of whom was a neighbor who tried to rescue the children. Authorities have declined to identify any of the five people injured or killed by the fire.
Crews from Scio, Jewett and Cadiz found the home fully involved when they arrived at the site at around 7:00 a.m. Wednesday.
No other details have been released. The State Fire Marshall's Office said an investigation is ongoing.